Channelpedia

Kv1.2 Channel

Published literature references

Introduction

Gene

Transcript

No data for this section

Ontology

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Interaction

  1. Grzywna Z. et al. Electrostatic interactions during Kv1.2 N-type inactivation: random-walk simulation.
    Eur. Biophys. J., 2009 Sep , 38 (1003-12).

  2. Morielli A. et al. Homeostatic regulation of Kv1.2 potassium channel trafficking by cyclic AMP.
    J. Biol. Chem., 2008 Feb 8 , 283 (3445-53).

  3. Doczi M. et al. An essential role for cortactin in the modulation of the potassium channel Kv1.2.
    Proc. Natl. Acad. Sci. U.S.A., 2007 Oct 30 , 104 (17412-7).

  4. Grunnet M. et al. The voltage-gated potassium channel subunit, Kv1.3, is expressed in epithelia.
    Biochim. Biophys. Acta, 2003 Sep 22 , 1616 (85-94).

  5. Zhu B. et al. Quinidine enhances and suppresses Kv1.2 from outside and inside the cell, respectively.
    J. Pharmacol. Exp. Ther., 1996 Nov , 279 (844-55).

Protein

  1. Qi Z. et al. Length-dependent regulation of the Kv1.2 channel activation by its C-terminus.
    Mol. Membr. Biol., 2009 Apr , 26 (186-93).

  2. Sokolowski B. et al. Cloning and developmental expression of Shaker potassium channels in the cochlea of the chicken.
    Brain Res. Mol. Brain Res., 2004 Feb 5 , 121 (70-85).

  3. Ishii K. et al. Hybrid potassium channels by tandem linkage of inactivating and non-inactivating subunits.
    J. Biol. Chem., 1994 Sep 30 , 269 (24138-42).

Structure

No data for this section

Distribution

Expression

  1. Clapcote S. et al. A new Kv1.2 channelopathy underlying cerebellar ataxia.
    J. Biol. Chem., 2010 Oct 15 , 285 (32160-73).

  2. Bertaso F. et al. Expression of voltage-gated K+ channels in human atrium.
    Basic Res. Cardiol., 2002 Nov , 97 (424-33).

  3. Scherer S. et al. Genetic dysmyelination alters the molecular architecture of the nodal region.
    J. Neurosci., 2002 Mar 1 , 22 (1726-37).

  4. Dolly J. et al. Subunit composition of Kv1 channels in human CNS.
    J. Neurochem., 1999 Aug , 73 (849-58).

  5. Yamamoto T. et al. Thyroid hormone regulates expression of shaker-related potassium channel mRNA in rat heart.
    Biochem. Biophys. Res. Commun., 1998 Apr 7 , 245 (226-30).

  6. Ishii K. et al. Absence of effects of class III antiarrhythmic agents on cloned cardiac K channels.
    Jpn. J. Pharmacol., 1993 Apr , 61 (371-3).

Functional

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Kinetics

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Model

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Credits

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