Channelpedia

Kir1.1 Channel

Published literature references

Introduction

Gene

  1. Zou S. et al. Role of potassium channel gene Kcnj10 in ethanol preference in C57bl/6J and DBA/2J mice.
    Alcohol. Clin. Exp. Res., 2009 Mar , 33 (394-9).

  2. Feldmann D. et al. Large deletion of the 5' end of the ROMK1 gene causes antenatal Bartter syndrome.
    J. Am. Soc. Nephrol., 1998 Dec , 9 (2357-9).

  3. Philipson L. et al. Alternative splicing of human inwardly rectifying K+ channel ROMK1 mRNA.
    Mol. Pharmacol., 1994 May , 45 (854-60).

Transcript

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Ontology

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Interaction

  1. Levitan E. et al. Specific and slow inhibition of the kir2.1 K+ channel by gambogic acid.
    J. Biol. Chem., 2009 Jun 5 , 284 (15432-8).

  2. Lee C. et al. Functional and structural characterization of PKA-mediated pHi gating of ROMK1 channels.
    J. Mol. Graph. Model., 2008 Oct , 27 (332-41).

  3. Liu J. et al. WNK1 kinase isoform switch regulates renal potassium excretion.
    Proc. Natl. Acad. Sci. U.S.A., 2006 May 30 , 103 (8558-63).

  4. Wang W. et al. Tetanus toxin abolishes exocytosis of ROMK1 induced by inhibition of protein tyrosine kinase.
    Am. J. Physiol. Renal Physiol., 2003 Mar , 284 (F510-7).

  5. Wang W. et al. K depletion increases protein tyrosine kinase-mediated phosphorylation of ROMK.
    Am. J. Physiol. Renal Physiol., 2002 Oct , 283 (F671-7).

  6. Graham D. et al. Regulation of ATP-sensitive potassium channel mRNA expression in rat kidney following ischemic injury.
    Biochem. Biophys. Res. Commun., 2000 Mar 16 , 269 (618-22).

  7. Satlin L. et al. Developmental expression of ROMK in rat kidney.
    Am. J. Physiol., 1999 Jun , 276 (F825-36).

  8. Chen X. et al. The A kinase anchoring protein is required for mediating the effect of protein kinase A on ROMK1 channels.
    Proc. Natl. Acad. Sci. U.S.A., 1998 Aug 18 , 95 (10274-8).

  9. Schneider S. et al. Imaging ROMK1 inwardly rectifying ATP-sensitive K+ channel protein using atomic force microscopy.
    Proc. Natl. Acad. Sci. U.S.A., 1996 Aug 6 , 93 (8756-60).

Protein

  1. Kaczorowski G. et al. Characterization of Kir1.1 channels with the use of a radiolabeled derivative of tertiapin.
    Biochemistry, 2006 Aug 22 , 45 (10129-39).

  2. Welling P. et al. Processing and transport of ROMK1 channel is temperature-sensitive.
    Biochem. Biophys. Res. Commun., 1999 Aug 2 , 261 (364-71).

  3. Chen C. et al. A snake toxin inhibitor of inward rectifier potassium channel ROMK1.
    Biochemistry, 1998 Oct 20 , 37 (14867-74).

  4. Hunter M. et al. Cation permeation and blockade of ROMK1, a cloned renal potassium channel.
    Pflugers Arch., 1997 Jun , 434 (151-8).

  5. Takahashi N. et al. A novel ATP-dependent inward rectifier potassium channel expressed predominantly in glial cells.
    J. Biol. Chem., 1995 Jul 7 , 270 (16339-46).

Structure

  1. Giebisch G. et al. Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K+ channel (ROMK).
    Proc. Natl. Acad. Sci. U.S.A., 2005 Jul 12 , 102 (9954-9).

Distribution

No data for this section

Expression

  1. Kaczorowski G. et al. Characterization of Kir1.1 channels with the use of a radiolabeled derivative of tertiapin.
    Biochemistry, 2006 Aug 22 , 45 (10129-39).

  2. Yang B. et al. Protein tyrosine kinase is expressed and regulates ROMK1 location in the cortical collecting duct.
    Am. J. Physiol. Renal Physiol., 2004 May , 286 (F881-92).

  3. Hunter M. et al. Biophysical effects of pore mutations of ROMK1.
    Clin. Sci., 2001 Aug , 101 (121-30).

  4. Soleimani M. et al. Possible molecular basis for changes in potassium handling in acute renal failure.
    Am. J. Kidney Dis., 2000 May , 35 (871-7).

  5. Palmer L. et al. Is the secretory K channel in the rat CCT ROMK?
    Am. J. Physiol., 1997 Sep , 273 (F404-10).

Functional

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Kinetics

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Model

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Credits

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