Channelpedia

Kir3.1 Channel

Published literature references

Introduction

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Gene

  1. Liao R. et al. Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP.
    J. Clin. Invest., 2008 Jan , 118 (259-71).

  2. Rosker C. et al. The GIRK1 brain variant GIRK1d and its functional impact on heteromultimeric GIRK channels.
    J. Recept. Signal Transduct. Res., 2007 , 27 (369-82).

Transcript

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Ontology

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Interaction

  1. Shi Y. et al. Molecular basis for the inhibition of G protein-coupled inward rectifier K(+) channels by protein kinase C.
    Proc. Natl. Acad. Sci. U.S.A., 2004 Jan 27 , 101 (1087-92).

  2. Xie L. et al. Molecular mechanism for ATP-dependent closure of the K+ channel Kir6.2.
    J. Physiol. (Lond.), 2003 Oct 1 , 552 (23-34).

  3. Marker C. et al. Contribution of the Kir3.1 subunit to the muscarinic-gated atrial potassium channel IKACh.
    J. Biol. Chem., 2002 Dec 13 , 277 (48282-8).

  4. Reuveny E. et al. Graded contribution of the Gbeta gamma binding domains to GIRK channel activation.
    Proc. Natl. Acad. Sci. U.S.A., 2002 Aug 6 , 99 (10783-8).

  5. Zhou W. et al. Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channels.
    Proc. Natl. Acad. Sci. U.S.A., 2001 May 22 , 98 (6482-7).

  6. Clapham D. et al. A switch mechanism for G beta gamma activation of I(KACh).
    J. Biol. Chem., 2000 Sep 22 , 275 (29709-16).

  7. Clapham D. et al. Gbeta binding to GIRK4 subunit is critical for G protein-gated K+ channel activation.
    J. Biol. Chem., 1998 Jul 3 , 273 (16946-52).

  8. Stevens E. et al. Molecular determinants for assembly of G-protein-activated inwardly rectifying K+ channels.
    J. Biol. Chem., 1997 Apr 18 , 272 (10823-30).

Protein

  1. Kaczorowski G. et al. Characterization of Kir1.1 channels with the use of a radiolabeled derivative of tertiapin.
    Biochemistry, 2006 Aug 22 , 45 (10129-39).

  2. Sansom M. et al. Identification of residues contributing to the ATP binding site of Kir6.2.
    EMBO J., 2003 Jun 16 , 22 (2903-12).

  3. Boyett M. et al. Expression, purification and spectroscopic studies of full-length Kir3.1 channel C-terminus.
    Biochim. Biophys. Acta, 2003 Dec 1 , 1652 (83-90).

  4. Clapham D. et al. Gbeta binding to GIRK4 subunit is critical for G protein-gated K+ channel activation.
    J. Biol. Chem., 1998 Jul 3 , 273 (16946-52).

  5. Macdonald J. et al. Cloning of a G protein-activated inwardly rectifying potassium channel from human cerebellum.
    Brain Res. Mol. Brain Res., 1996 Jul , 39 (23-30).

Structure

Distribution

Expression

  1. Yu Y. et al. Inwardly rectifying potassium channels in rat retinal ganglion cells.
    Eur. J. Neurosci., 2004 Aug , 20 (956-64).

  2. Tong X. et al. [The expression levels of GIRK1 and IRK1 in memory deficit rats]
    Yao Xue Xue Bao, 2001 Jul , 36 (485-8).

Functional

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Kinetics

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Model

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Credits

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See all the possible references for Kir3.1