Channelpedia

PubMed 22986435


Referenced in: none

Automatically associated channels: Kir4.1



Title: Disease mechanisms in MS: the potassium channel KIR4.1--a potential autoantigen in MS.

Authors: Michael K Racke

Journal, date & volume: Nat Rev Neurol, 2012 Nov 5 , 8, 595-6

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/22986435


Abstract
Multiple sclerosis is an inflammatory, demyelinating disease in which antigens of the myelin sheath have been considered the autoimmune target. A recent study suggests that the potassium channel KIR4.1 is another potential autoantigen in some patients with multiple sclerosis, and might also be a target in other demyelinating diseases.