Referenced in: none

Automatically associated channels: Kv4.1

Title: Slips, leaks and channels in glutamate transporters.

Authors: Robert J Vandenberg, Shiwei Huang, Renae M Ryan

Journal, date & volume: Channels (Austin), 2008 Jan-Feb , 2, 51-8

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/18690049

Abstract
Glutamate transporters are unusual proteins in that they can function as both a transporter and a chloride channel. With the recent determination of the crystal structure of an archaeal aspartate transporter it is now possible to begin to put together a physical picture of how these proteins are able to carry out their dual functions. In this review we shall discuss our current understanding of the functional states of glutamate transporters and how they may arise. We will also discuss some of the alternate conducting states of glutamate transporters and provide definitions of the various states.