Referenced in: none

Automatically associated channels: Kv4.1 , Slo1

Title: Voltage-activated potassium currents in isolated motor neurons from the jellyfish Polyorchis penicillatus.

Authors: J Przysiezniak, A N Spencer

Journal, date & volume: J. Neurophysiol., 1994 Aug , 72, 1010-9

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/7983506

Abstract
1. We describe two voltage-activated potassium currents in the swim motor neurons (SMNs) of the hydrozoan jellyfish, Polyorchis penicillatus. Recordings from neurons isolated in primary cultures were made using the tight-seal, whole-cell technique. 2. One current, IK-fast, turned on rapidly (time to peak = 6-15 ms), was half-activated at -10 to 0 mV, decayed with two exponential phases (tau were approximately 70 ms and approximately 1 s), and was half-inactivated by prepulses around -53 mV. It likely plays an important role in regulating the duration of SMN action potentials. IK-fast has features shared by delayed rectifiers and A-like currents in other invertebrates and vertebrates. 3. Another current, IK-slow, elicited from a holding potential of -30 mV, exhibited a slow onset (tau = 65-250 ms), was half-activated approximately +24 mV, exhibited a shallower voltage dependence than IK-fast, and did not inactivate. It was slower than most known delayed rectifiers.